الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 102 |  |  |
| | | from | 102 | | |
Abstract
Chronic Renal Failure (CRF) is a progressive irreversible kidney failure that leads to failure of the body to maintain metabolic and electrolytic balance leading to metabolic acidosis, electrolyte disturbance and anemia.
The main causes of CRF are diabetes, hypertention, glomerulonephritis and poly cystic kidney disease.
Haemodialysis is the main frequent treatment for CRF. However, it has a number of restrictions and modifications which have a detrimental impact on the quality of patient‘s life and affect individuals‘ psychological and physical well-being.
Psychological disturbances include a general feeling of unwellness major disturbance of life style to comply with treatment regimen including dialysis schedule , diet prescription , water restriction and fear of morbidity, disability and shortened life span.
Depression has been studied extensively in patient on chronic dialysis and much efforts have been done to diagnose and define different treatment options for depressed patient on chronic dialysis.
Evidence indicates that anxiety is also common in patients with chronic dialysis however less studies have been done, more attention must be paid to approach diagnosis and treatment of anxiety in patient with ESRD.
In our study; we aimed at Examining the prevalence of depressive and anxiety disorders in patients with chronic kidney diseases,Studying the relationship between the severity of psychiatric symptomology and severity of renal impairment (clinically and laboratory).
In our stud; we collected patients diagnosed with chronic kidney diseases and end-stage renal disease from patients attended dialysis unit in Minia health insurance hospital and outpatient internal medicine clinic in Minia health insurance hospital.
Those patients included; both genders, Patients suffering from chronic kidney diseases and Patients who are on dialysis or following up in outpatient clinic, and exclude patients of major psychiatric disorders before the onset of renal impairment.
Patient was recruited and full socio-demographic characteristics will be collected including: Age, sex, residence, marital status, occupation and history of substance use including smoking and addictive substances and birth order, Complete psychiatric sheet was been applied including: psychiatric complaint, history of present illness, past psychiatric history, Family history of psychiatric disorders and mental state examination, Subjects was interviewed using the following tools:
a- Mini-international neuropsychiatric interview (Sheehan et al,1997). b- Beck Depression Inventory (Beck et al, 1961).
c- Hamilton Rating Scale of depression and anxiety (Hamilton et al,1960). d- Taylor Anxiety Scale (Taylor et al, 1953).
4-Blood sample will be collected then tested for CBC ,lipid profile ,renal functions and serum electrolytes.
We divided patients into following groups:
group A: 30 patients on dialysis more than 6 months.
- group B: 31 patients on dialysis less than 6 months.
- group C: 32 patients with chronic kidney diseases without dialysis.
-group D: 30 Control group
* then we compared these groups according to results of the tools mentioned
earlier.
In our study; we found that the more the duration of the kidney disease, the more increase in severity of psychological disorder in patients of CKD, Depression presented in various degrees in most of our patients according to the used psychological tools in our study, Anxiety presented in various degrees in most of our patients according to the used psychological tools in our study and Electrolyte disturbance cause psychological disorder in patients of CKD and ESRD directly and indirectly.