الفهرس | Only 14 pages are availabe for public view |
Abstract We concluded that S. haemolyticus carries an inclusive set of genes that code for different virulence factors such as toxins, enzymes and adhesion proteins. Our results provide a contribution for a better understanding of the pathomechanisms of S. haemolyticus infections and fill a gap in the literature regarding the CoNS. Based on our observations, microbiology laboratories should consider S. haemolyticus as a critical opportunistic pathogen and infections caused by this organism, particularly in critical ill patients, should be seriously managed. Additional experiments are planned to study the expression of these genes upon infection of the PHSF cells and the role of these genes in invasion, intracellular survival and establishment of infection in the host cells. These factors may contribute to the bacteria’s ability to spread through tissues and the pathological damage associated with DFU. |