الفهرس 
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Abstract
Propofol is today considered the most common
intravenous drug for the induction of general anesthesia. It is a
drug with Phenol structure whose common complication is pain
at the injection site as well as low blood pressure.
This study was carried-out for Comparison of treatment
with granisetron versus lignocaine with respect to improvement
of pain induced by injection of propofol, in patient admitted for
elective surgery under general anesthesia.
This study was carried-out on 284 patients belonging to
American Society of Anesthesiologists (ASA) physical status
(PS) 1 and 2, of either sex, aged 18–60 years, scheduled for
various elective surgical procedures under general anesthesia.
The patients divided into 2 groups; group 1 that consist
of 142 patients which received injection of intravenous
propofol (1-2 mg/kg) after injection with 1 ml of 2%
lignocaine. group 2 consist of another 142 which received
injection of intravenous propofol (1-2 mg/kg) after injection
with 1 ml of 1ml of granisetron (1 mg/ml).
Our results concluded that:
1. The demographic data (age, body weight, sex ratio),
physical status and type of surgery are not differ
significantly (P > 0.05) among the two groups of this study.2. Our results on the heart rate, Systolic arterial blood pressure
and diastolic arterial blood pressure showed no statistical
significance after injection of lignocaine, granisetron and
propofol at different points of time.
3. The moderate and severe pain observed after different points
of time from the injection of propofol can be reduced by
injection of granisetron or lignocaine before propofol
administration.