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Abstract This was a prospective observational study aimed to study the role of hysteroscopy in repeated IVF/ICSI failure and its impact on subsequent trials. 50 patients were enrolled randomly from assisted reproductive unit in Tanta University. We included only patients with history of two or more failed IVF/ICSI despite of delivery of at least two good embyos. Any patient with age more than 38 years, BMI more than 29, has uterine abnormality by US or has any systemic or endocrilnal disease was excluded from the study. Informed written consent was taken from every included patient. After full history and examination, all patients were subjected to 4D US examination with same device (Siemens acuson X300). Then from day 7 day 11 from menstruation hysteroscopy was done to all patients using saline as a distention medium. Results showed that by 4D US, 82% had unremarkable findings. According to abnormal findings, the number of patients that had polyp, endometritis, myoma, and septum was 4,1,3 and 1 patients respectively and those represented 8%, 2%, 6% and 2% respectively. while by hysteroscopy, 60% had unremarkable findings. According to abnormal findings, the number of patients that had polyp, endometritis, myoma, and septum, narrow cavity, short cevix and adhesive band was 43,7,2,3,3,1 and 1 and 1 patients respectively and those represented 6%, 14%, 4% , 6%, 6% , 2% and 2% respectively. |