الفهرس 
Introduction & Aim of the StudyOnly 14 pages are availabe for public view
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Abstract
Background: Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, with excellent survival outcomes. Recognition of the adverse effects of treatment for ALL has resulted in a growth of interest in quality of life (QOL) assessment of children. The aim of the work: To evaluate sleep disorders and health related quality of life in pediatric ALL survivors. Type of study: observational cross-sectional study. Patients and Methods: This study was done on 25 survivors from ALL attending outpatient clinic in Mansoura Oncology Center, Mansoura University, aged from 6 to 18 years and ended last chemotherapy at least 3-6 months ago. Psychological assessment was done. Concept of health related quality of life needs to be understood by the general population, researchers, medical and health care professionals and the patients themselves to make it a global concept. It is required to value the patient’s perception about his illness and alter the treatment plan accordingly. Sleep assessment was done and health-related quality of life. Results: The mean total CSHQ for all age groups was poor. Age showed significant negative correlations with bedtime resistance, sleep anxiety. Otherwise, no significant correlations were found regarding age and time after treatment with CSHQ score in all studied children. The total CSHQ score showed significant negative correlation with communication, procedural total PedsQL in child reports; communications, worries and total PedsQL in parent reports. Conclusion: Adequate and good quality sleep is very important for children. Sleep impacts children’s growth and development and also cognitive functions, learnings and attention. Impaired sleep may be a contributing determinant. Consequently, enhanced counseling and treatment of sleep problems might improve QoL. Recommendations: It is important to conduct more extensive studies to confirm these findings and provide more detailed information on the relationship between sleep and QoL, and on factors affecting sleep in pediatric ALL and in children with cancer in general.