الفهرس | Only 14 pages are availabe for public view |
Abstract Summary The incidence of AKI in the intensive care unit (ICU) was noted to be 57%, with sepsis being attributed as the etiology in 41% of the cases. Nowadays Doppler ultrasound is rapidly gaining ground as a screening tool in critically ill patients. The performance of cardiac, lung and abdominal ultrasound in patients after cardiac arrest, major operations and during shock has become standard policy. However, renal ultrasound, which could be easily incorporated in this screening, is not commonly performed. Our study was an observational cohort study that intended to test the ability of Renal resistive index (RRI) measurement by Doppler Ultra Sound to predict outcome of AKI whether it is transient or persistent in septic patients. And to test the ability of RRI to predict mortality in this group of patients. This study conducted on 40 patients admitted to critical care department of Beni-Suef university hospital diagnosed as having sepsis and AKI. Patients were defined as having sepsis according to the definition of the European Society of Intensive Care Medicine.(52) Also patients were definied as having AKI according to KDIGO criteria.(25) Renal resistive index was measured on ICU admission and 48h from admission. Our study demonstrated a significant increase of RRI in cases with persistent AKI in comparison to cases with transient AKI (P. value< 0.05). ROC curve calculation for prediction need of dialysis: cut off value of RRI˃0.64 on admission had the highest area under curve(AUC) (0.959) predicted persistent AKI (P. value< 0.05). Cut off value of RRI ˃0.64 after 48h had the highest AUC (0.987) predicted persistent AKI (P. value< 0.05). Also, our study demonstrated a significant increase in APACHE ӀӀӀ score in patients with high RI value (P. < 0.05). In our study there was significant positive correlation between RI and Lactate level (P.<0.05). In our study there was significant positive correlation between RI and mean creatinine (P.<0.04). |