الفهرس 
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Abstract
Sheep pox, goat pox and lumpy skin are serious diseases that cause a huge economic loss in Egypt. Sheep pox, goat pox, and lumpy skin are endemic diseases since their discovery in Egypt. Despite cross-protection between genus Capripox viruses, vaccination with living attenuated homologous and heterologous vaccines is the only effective way to control these diseases in Egypt. Although, the regular and prompt vaccination against Capripox virus diseases in Egypt, problems of vaccination failure and short duration of protection can occur. In this study, heterologous attenuated sheep pox vaccine was evaluated in cattle and goat, also, homologous Neethling vaccine and sheep pox vaccine were evaluated in cattle and sheep, respectively. All tested vaccines were evaluated for humoral and cellular immunity using ELISA, IFN-γ, lysozymes, and nitric oxide production in serum at the field conditions .