الفهرس 
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Abstract
Acute kidney injury (AKI) is now recognized as a major public health problem affecting millions of patient’s worlds- wide and leading to decreased survival, increased progression of underlying chronic kidney disease (CKD), and sometimes to new onset of CKD. Early detection and management pf AKI is highly important to prevent its complications, hospital stay deration and mortality rate. Aim of the work: The objective of this study is to evaluate the risk of AKI in critically ill patients stratified by various admission serum albumin levels. - Subjects and methods: This prospective cohort study was conducted on critically ill patients in Medical critical care units, Mansoura University Hospitals over a period of One year, starting from December 2019 till December 2020. This study involved 160 ICU patients divided into two groups: group A: AKI group (N = 79). group B: Non-AKI group (N = 81). All cases have renal U/S. All selected patients were subjected to history taking and physical examination. Blood samples were collected for CBC, liver functions, AFP ABG, electrolytes and serum creatinine. Results: In this study, 160 cases were divided in two groups acc to presence or absence of AKI. This study proves that Hypoalbuminemia especially serum albumin cut-off ≤3 mg/dl in this study was statistically significant predictor for development of AKI in Univariate or multivariate analysis. This study suggests that determinations of serum albumin may be of value in identifying patients at higher risk for AKI as well as death following the development of AKI. A lot of studies have established that hypoalbuminemia as an independent risk factor for AKI. - Conclusion: This study established that Albumin is a significant independent risk factor for Aki development.