الفهرس 
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Abstract
The diagnosis of spontaneous bacterial peritonitis (SBP) is based on
PMNs exceeding 250/μL in ascetic fluid.
The aim of the study was to evaluate MPV as diagnostic marker for
detecting SBP and whether it could be used as prognostic factor to follow up
response to treatment of SBP.
A total of forty patients with cirrhosis and ascites were enrolled in this
study. According to ascetic fluid analysis, they were divided into a SBP group
including twenty patients, and a non-SBP group of twenty patients.
All patients were subjected to full clinical assessment, laboratory test
evaluation (Complete blood picture including Mean Platelet Volume, liver
function tests, kidney function tests, coagulation profile, ascetic fluid analysis
and ascetic fluid culture),Abdominal ultrasonography and calculation of Child
Pugh score.
Patients with SBP were treated and follow up MPV was done after five
days. The ability of MPV values to predict SBP in cirrhotic patients was
analyzed using receiver operator characteristic (ROC) curve analysis.
Results revealed a statistically significant increase in MPV level in
cirrhotic patients with SBP compared to cirrhotic patients without SBP (p <
0.001). A statistically significant directly proportionate increase was observed in
the SBP group between MPV and both ESR and C-reactive protein (CRP). It
was found that the optimum MPV level cut-off point for cirrhotic patients with
SBP was 8.4fl, with a sensitivity, specificity, negative predictive value (NPV),Summary