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Abstract The aim of radiation therapy is to give the subject a therapeutic dose of radiation while limiting the side effects induced by the application of the dose to the tissues and vital organs around it. The continuing search to reach an optimum dose delivery has led the field of radiation therapy to create innovative methods that integrate scientific advancements. New methods include three-dimensional conformal radiation therapy (3D-CRT), intensitymodulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) are widely used in radiation therapy today in the treatment of cancers. In the IMRT and VMAT techniques and 3D conformal techniques, clinical and dosimetric findings of IMRT in brain tumors were compared between coplanar and non-coplanar. Superior dose conformity and homogeneity were shown by IMRT. Furthermore, IMRT reduced normal tissue doses, notably in cases where vital structures such as the optic nerves and the brain stem were affected by the target. The focus of this work was dosimetric assessment research on the effects of using a non-coplanar procedure relative to the coplanar IMRT treatment plans for brain tumor patients. This study included 15 patients with brain cancer. For each patient, two treatment plans (coplanar and non-coplanar IMRT) using energies (6MV) is done and Dose-volumehistogram was analyzed (DVH). Our results showed that: The mean dose received by PTV D5%, D95%, D98%, and D106% were insignificantly different between the two techniques. Regarding organ at risk, dose comparison for two techniques showed insignificant difference. There were also no major discrepancies in homogeneity index (HI) and conformation number (CN) between the two techniques. The plan quality and treatment efficiency parameters comparison showed: no statistically significant differences in the coplanar and non-coplanar IMRT plans in terms of PTV coverage and OARs. |