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Abstract SLE is an autoimmune disease caused by many different causes, such as environmental and genetic factors, which cause the possibility of infection with SLE. And the period of infection with the disease reaches for life, as until now there is no effective treatment for the disease. In Egypt there is a large percentage of people infected with the disease, despite the presence of this number, there is no global classification or statistics that have been published to know the number of people infected with the disease in Egypt, but what has been published in the number of infected people in the Middle East. In recent times, there has been growing attention in the usage of bioelectric impedance analysis technology to study different body components in many diseases such as cancer and arthritis and to study the ideal body weight, but this study is the first one in the world to study body components using the bioelectric impedance analysis device for subjects with SLE. As the device can designate body compounds such as the mass of water inside and outside the cell and the total weight of water in the body. It can also estimate proteins, bone masses, resistance, electrical impedance, and capacity to five parts of the body, the device divides the body into five parts, which are the RA, LA, TR, and RL, and LL. The device consists of 8 metal plates that respond to the changes that occur in the body’s cells. The device has several versions, but the version used in this study is In- Body 720, Biospace Co., Ltd., Seoul, S. Korea The objectives of the study were to use the bioelectric impedance analysis device to study the body components of SLE subjects and to study the changes made to the body components as a result of the disease in the post-disease stage. The study was carried out on 50 donors, who were divided into two groups. The first group (n = 25) includes subjects diagnosed with SLE at the Medical Research Institute, Alexandria University, The second group (n = 25) represents the control group, which is identical to the first group in age and social level. The analyzes were performed for all donors were, complete blood analysis, C-reactive protein (CRP), Analysis of An Erythrocyte Sedimentation Rate (ESR), and body composition analysis using the In-Body 720, Biospace Co., Ltd., Seoul, S. Korea It has been shown that the bioelectric Impedance Analyzer has advantages such as measuring time, which takes 120 seconds for each donor, easy to use, does not need to process samples, and provides a safe method. The device was able to identify the body components of all donors and determine their body components. The most important results obtained were that SLE causes an increase in most of the body compounds, and this supports the fact that the body compounds of SLE subjects differ from those of healthy ones. Therefore, we recommend using the electro-electrical impedance analyzer as an accurate method for identifying body compounds for SLE subjects, as the analysis is easy to implement, accurate, reliable, and fast. This method requires the subject to simply stand on the device without any surgical intervention or taking blood samples from the subject |