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العنوان
Study of urinary monocyte chemoattractant protein-1(MCP-1) level in morbidly obese patients before and after bariatric surgeries and its relation to renal function /
المؤلف
Elmamlook, Shimaa Mounir Abdelhalim.
هيئة الاعداد
باحث / شيماء منير عبدالحليم المملوك
مشرف / علاء عبدالعزيز صبرى
مشرف / أحمد بهى الدين ابراهيم
مشرف / محمد أحمد الرفاعي
الموضوع
Obesity - Surgery. Obesity - Complications.
تاريخ النشر
2021.
عدد الصفحات
Online sources (145 pages) :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة المنصورة - كلية الطب - قسم الباطنة العامة
الفهرس
Only 14 pages are availabe for public view

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from 167

Abstract

Obesity is a chronic worldwide health problem, which affect more than 600 million person and expected to increase in the next decade by about 40%. Obesity has several complications on the body as DM, hypertension, ischemic heart disease, dyslipidemia, GERD and obstructive sleep apnea. In addition, obesity has hazardous effect on the kidney as ORG, FSGS, diabetic nephropathy and renal stones. In this trial 40 patients were assessed for obesity parameters (clinical, laboratory) and to assess the level of renal inflammatory marker (MCP-1) in morbid obese patients before and after bariatric surgeries and to study if there any possible relation between the MCP1 levels and renal function before and after surgery. Increase the GFR level and albuminuria before the surgery. There was significantly decrease in urinary MCP-1 and MCP-1/ cr ratio level in urine after the surgery while there was no correlation between MCP-1 and renal function. Our trial showed no significant deference in MCP-1 and MCP-1/cr level between sleeve gastrectomy and minigastric bypass.