الفهرس 
Anatomy of the brain
Pathophysiology of EpilepsyOnly 14 pages are availabe for public view
 |  | from | 145 |  |  |
| | | from | 145 | | |
Abstract
SUMMARY Epilepsies are among the most common neurological problems. Magnetic resonance techniques are becoming increasingly important in localizing the seizure focus and for the management of those patients. Importantly, magnetic resonance (MR) tractography based on diffusiontensor imaging (DTI) is greatly involved in clinical diagnostic studies to detect subtle abnormalities encompassing the lesion seen on conventional MRI with normal-appearing white matter. The aim of this study is identifying the added value of diffusion tensor MRI and tractography in the preoperative assessment of epileptogenic focus. The inclusion criteria for this study included patients who were diagnosed clinically and/or electro-encephalography to have epilepsy. On the other hand the exclusion criteria included people with pacemakers, cochlear implants, deep brain stimulators, and also claustrophobic patients. This prospective study was conducted on 20 patients with clinical manifestations of epilepsy and another 10 age and sex-matched healthy control group to identify the differences in the white matter connectivity in epileptic patients relative to the healthy control group. This study was carried out during a period from March 2018 till April 2021 and was approved by the research ethical committee, faculty of medicine, Tanta University. All patients were subjected to the followings: informed consent obtained from all patients, full clinical history taking, neurological examination, EEG, conventional MRI, as well as DTI and tractography. MRIs were performed by using a standard 1.5 Tesla unit (signal high speed, GE Signa Explorer) at MRI unit of Radio-diagnosis Department,