الفهرس 
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Abstract
Systemic lupus erythematosus (SLE) is a chronic inflammatory AI disease with unrecognized cause that shows various clinical symptoms and sign, various illness, and prognosis course. Consequently, the SLE cases assessment is not easy in the daily practice for the physician. Additionally, the management of the cases suffering from this disease can be different in accordance with the activity of the disease (Oehadian et al., 2013). It has been reported that systemic lupus erythematosus (SLE) can be classified as mild or severe and life-threatening. In the cases suffering from severe activity of the disease, lymphopenia and leukopenia can be present (Nikolopoulos et al., 2019). It has been stated that the onset of systemic lupus erythematosus (SLE) in the Childhood period is recognized to be associated with a poorer prognosis than the disease which starts in the adult period in forms of the activity of the disease, the damage of organs, and the related mortality rates (Kamphuis and Silverman, 2010). Several laboratory and clinical parameters can be utilized to assess the activity of the disease. The laboratory parameters are increased binding of DNA, low complement, leukopenia and thrombocytopenia (Klecka et al., 2018). It has been reported that Pregnancy can lead to predisposition of cases to a lupus flare, particularly in the condition of the disease being not sufficiently controlled at the conception onset. Consequently, cases have been recommended not to be pregnant until SLE is quiescent for 0.5 year (Attia et al., 2019).