الفهرس 
Chronic kidney disease and hemodialysisOnly 14 pages are availabe for public view
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Abstract
Chronic kidney disease (CKD) is a global problem, gaining
importance day after another. CKD burden increases due to increased
prevalence of hypertension, diabetes Mellitus, and cardiovascular
diseases.
CVDs are the major cause of death in hemodialysis patients
accounting for up to 45% of all deaths.
Speckle-tracking echocardiography has emerged as a quantitative
technique for evaluating myocardial function.
The present study aimed at assessing the right ventricular functions
in chronic hemodialysis patients using two-dimensional speckle tracking
echocardiography as a noninvasive and quantitative method of
assessment.
This study included 100 patients with chronic hemodialysis
patients (group I) referred to the cardiology department, Benha University
Hospital and were compared with 20 healthy individuals (group II) of
matched age and gender.
They were assessed for baseline characteristics, admission data,
electrocardiography and echocardiographic parameters.
Patients with hemodialysis had greater RA volumes (maximal and
minimal), greater RV areas (end systolic and end diastolic), volumes (end
systolic and end diastolic) and greater estimated pulmonary artery systolic
pressure(PASP) but lower RV fractional area change (FAC) and lower
tricuspid annular plane excursion (TAPSE).
There was no significant statistical difference between the 2
groups regarding left ventricular ejection fraction, Left ventricular end
Summary
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diastolic volume (LVEDV), left ventricular end systolic volume
(LVESV).
Right ventricular and atrial global longitudinal strain (RAGLS%
and RVGLS %) were significantly reduced in hemodialysis patients.
Right ventricular global longitudinal strain (RVLS) showed a
significant negative correlation with age, RV end-diastolic and end
systolic volumes, RV diameters (longitudinal diameter and mid cavity
diameter), RA maximal volume and tricuspid E∕A ratio. While it showed
significant positive correlation with FAC and LV ejection fraction.
Tricuspid valve E wave velocity and tricuspid E/A ratio were
significantly decreased in group I patients. While tricuspid valve A wave
velocity was significantly increased in group I patients.
Tricuspid valve E\ and S velocity were significantly decreased in
group I patients while tricuspid valve A\ velocity was significantly
increased in group I patients. MPI was significantly increased in group I
patients.
Right atrial global longitudinal strain (RALS) showed a significant
negative correlation with RA maximal volume and positive correlation
with RV end diastolic area and RA transverse diameter.