الفهرس 
1. INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 193 |  |  |
| | | from | 193 | | |
Abstract
Hyperlipidemia has been shown to be a strong risk factor for coronary heart diseases indication and risk factor for early atherosclerosis prior to the appearance of over atherosclerotic changes in the vascular wall.
VCO virgin coconut oil is produced from fresh coconut which is produced without high heating, so that the important content in coconut oil can be maintained. VCO has a rich content of medium chain fatty acids (MCFAs), predominantly lauric acid(c12:0) others include caproic acid, caprylic acid and capric acid. VCO is known for its medicinal properties as anti-inflammatory, analgesic and hypothermic properties, antimicrobial and VCO showed significant anticoagulant effect. In addition to many medicinal benefits of VCO which have been mentioned, it has beneficial effects on lipid profile by reducing levels of total cholesterol, LDL and VLDL so VCO had the ability to reduce hyperlipidemia.
Adeyemi et al., (2020) reported that treating hypercholeterolemic male rats with VCO for four weeks by using different concentrations of it (VCO 200 +VCO 400 and +VCO 600) it significantly reduced TC, TG and LDL-c.
There have also been many scientific reports on the health benefits and nutritional potential of the bioactive compounds of sunflower oil. It is the non-volatile oil extracted from sunflower (Helianthus annus) seeds of the Asteraceae family. The sunflower oil is interesting by its content in linoleic acid(C18:2(n-6)). It is a mixture of monounsaturated and polyunsaturated fats with low levels of saturated fats. Sunflower powderis characterized by a high concentration of linoleic acid, moderate level of oleic acid, very low level of linoleic acid, less than 15% of the saturated fatty acids, palmitic and stearic acids and usually less than 1% of acids with fewer than 16 or more than 18 carbon atoms. While lauric, arachidic, behenic, lihnoceric and eicosenoic acids may be present, these acids are of little practical importance. Traces of oxygenated fatty acids also have been found in some sunflower seeds stored for prolonged period. The powderand herb tincture is employing for anti-inflammatory, antioxidant, antitumor, anti-asthmatic, antigen, antipyretic, astringent, anti-hypoglycemic effect, cathartic, diuretic, stimulant, vermifuge and antimicrobial activities. Sunflower oil has beneficial effects on lipid profile by reducing total triglycerides and increasing HDL levels Basak et al. (2017), who found that the group treated with sunflower oil differed significantly (P ≤ 0.05) from the control group, and the total triglycerides decreased significantly (P ≤ 0.05) HDL was significantly increased (P ≤ 0.05) in the treated group compared with the control group.
Matthiola incana seeds is an oilseed of great importance. The stock flower (Matthiola incana, L.) is a species from the Brassicaceae family. It is an ornamental plant. Seeds of the stock flower contain oil rich in linolenic acid (55-65%) that is of medicinal importance. the seeds of Matthiola incana acted as a diuretic, expectorant, tonic, stomach tonic and also worked as a cancer treatment. In addition to it has beneficial effects on lipid profile by reducing TC, TG and LDL-c as M. Incana seeds contained Oil rich (55--65%) in omega-3 (n - 3) linolenic acid and elicited a beneficial effect when fed to animals by reducing cholesterol Yaniv et al.,(1999) reported that treating hypercholeterolemic male rats with M. Incana oil for 6 weeks compared with rats fed a diet containing coconut oil or sunflower oil it significantly reduced TC, TG and LDL-c as M. Incana seeds contained Oil rich (55--65%) in omega-3 (n - 3) linolenic acid and elicited a beneficial effect when fed to animals by reducing cholesterol levels.
This study was conducted to study and compare the effect of (omega 3) from Matthiola incana seed with the effect of some other oils such as virgin coconut oil and sunflower oil on lipids profile. The effect of different concentrations of Matthiola incana powder(2.5% and 5%), virgin coconut oil (1% and 2%) and sunflower oil (1% and 2%) on hyperlipidemic rats were evaluated on biological, biochemical, and histological changes of hyperlipidemic male albino rats. Some physiological characteristics such as (serum lipid profile, liver functions, kidney functions, serum glucose levels, complete blood count, body weight gain, feed intake, feed efficiency ratio and internal organs weight) in tested albino rats were also measured.
Forty adult male white albino, 10 weeks age, weighting (150±10 g) was used in this experiment. All rats were fed on standard diet for 7 days for adaptation.
Rats were randomly divided into two main groups:
The first group, negative control group (n = 5), fed standard diet only.
The second main group Hyperlipidemic rats (n=35).