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العنوان
Synthesis and reactions of 4,6-O-benzylidene-α-methyl-Dglucopyranoside and Evaluation of their Biological activity =
المؤلف
Ali, Walaa Ali Abd El Halim.
هيئة الاعداد
باحث / Walaa Ali Abd El Halim Ali
مشرف / Dr. Mohamed Mohamed El Sadek
مشرف / Dr. Mohamed Abd El-Zaher Mostafa
مشرف / Prof. Dr. Seham Yassen Hassan
الموضوع
Biology. Benzylidene.
تاريخ النشر
2021.
عدد الصفحات
302 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الكيمياء
تاريخ الإجازة
2/10/2021
مكان الإجازة
جامعة الاسكندريه - كلية العلوم - Chemistry
الفهرس
Only 14 pages are availabe for public view

from 317

from 317

Abstract

This thesis comprises five chapters. The first is the introduction which reviewed the recent methods in the literature for synthesis and reactions of Methyl 4,6-O-benzylidene-α-Dglucopyranoside from carbohydrate precursors.The second chapter involves a detailed discussion of the results obtained by the candidate throughout the work; in which methyl 4,6-O-benzylidene-α-D-glucopyranoside 80 was prepared.Acetylation of 80 with a mixture of acetic anhydride and pyridine furnished the 4,6-O.81 diacetate-2,3 glucopyranoside-D-methyl-α-benzylidene 82 diol-2,3 glucopyranoside-D-methyl-α-benzylidene-O-4,6 gave 80 Periodate oxidation of
Condensation of the diol 82 with a number of acylhydrazines in acidic medium +glucopyranoside 83,methyl-4,6-O-benzylidene-3-deoxy3-(p-chlorophenylazo)-α-Dglucopyranoside 84,methyl -4,6-O benzylidene-3-deoxy3-(p-methylphenylazo)-α-Dglucopyranoside 85 and methyl -4,6-O-benzylidene-3-deoxy.