الفهرس 
Ulcerative colitisOnly 14 pages are availabe for public view
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Abstract
Background: Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) characterized by alternating periods of remission and relapse. As ulcerative colitis (UC) is a disease affecting the superficial layers of colonic wall, mucosal healing is, theoretically, a more achievable result of therapy compared with the transmural inflammation of Crohn’s disease; thus, endoscopic response is often a target in clinical trials..
Aim of the Work: The aim of this study is to to compare colonoscopy versus bowel ultrasound in assessment of disease activity and severity in patients with ulcerative colitis
Methodology: All data were collected, tabulated and statistically analyzed using SPSS 22.0 for windows (SPSS Inc., Chicago, IL, USA) & MedCalc 13 for windows (MedCalc Software bvba, Ostend, Belgium).
Data were tested for normal distribution using the Shapiro Walk test. Qualitative data were represented as frequencies and relative percentages. Chi square test (χ2) and Fisher exact was used to calculate difference between qualitative variables as indicated. Quantitative data were expressed as mean ± SD (Standard deviation) for parametric and median and range for non-parametric data.
Results: Thiscase control study was conducted on 90 patients (60 of them were diagnosed with ulcerative colitis) divided into 2 groups
group I (n=30) (control group) healthy individuals, matched for age and gender.
group II (n=60) Active and inactive (in remission) ulcerative colitis patients.
The patients were recruited from Internal Medicine and Gastroenterology outpatient clinics in Ain Shams University.
Conclusion: Bowel ultrasound may represent a useful first-line, non-invasive tool for assessing endoscopic activity and severity, and may be helpful to determine in a rapid manner whether a significant flare has occurred and to guide the management of UC patients, delaying or avoiding colonoscopy when it is not needed.