الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Inflammatory conditions and autoimmunity has a great burden on male fertility, and has been studies with more enthusiasm in last decades.
The testis is one of highly immune-privileged systems and it is under strict balance between inflammatory and anti-inflammatory conditions with high number of mediators and cytokines.
One of the major cytokines that is involved in inflammatory and autoimmune diseases is IL-17.
It has been found that IL-17 is affecting semen quality in terms of sperm motility and sperm vitality, also increases in some inflammatory condition inside the testis, and even in patient with varicosele.
In this study we tried to correlate between IL-17 level in infertile patients and seminal parameters.
This study was carried on 50 infertile patients who attend to the Outpatient Clinic of Dermatology, Venereology and Andrology Department, Alexandria Main University Hospital, and 20 fertile males as a control.
We found that IL-17 levels were higher in infertile patients, we found that the mean of IL17 value in patient group is 2.42 ± 2.43ng/l with highest value is 8.75ng/l and lowest is 0, while in control group the mean is 0.28 ± 0.66ng/l with highest value is 2.34 and lowest 0. All these differences are statistically significant.
In comparing IL-17 level to seminal parameters including semen volume, sperm concentration, total motility, progressive motility, sperm vitality, PH and sperm morphology no statistically significant difference has been found.
On the other hand, statistically significant differences have been found on comparing il-17 level to leucocyte count on semen, also statistically significant differences have been found while comparing IL-17 level to the presence of varicosele.