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Abstract Background: Patients with chronic kidney disease (CKD), especially those on regular hemodialysis, have unique Mineral and endocrine disturbances. Vascular calcification is a dynamic process influenced by bone kidney disease, as well as an imbalance between promoters and inhibitors of extra-osseous bone formation. Calcification is defined as the accumulation of calcium salts in tissues. This is a specific type of mineralization, which in contrast to calcification involves the deposition of any mineral. Aim of the Work: To determine abdominal blood vessels calcification in hemodialysis patients and its relation to fetuin A plasma level. Patients and Methods: This study included 60 patients (30 case and 30 control) admitted to Mansoura university hospitals. The patients were included in this study, all are End-stage renal disease (ESRD) patients on regular hemodialysis (HD) (4 Hours- 3 times weekly) for at least 3 month after obtaining informed conset from all patients). Results: Our study showed non significant negative correlation between fetuin A and aortic calcium score . Conclusion: High serum fetuin-A level was shown to be protective factor against vascular calcification and is associated with lower severity of abdominal aortic calcifications in regular hemodialysis patients. |