الفهرس 
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Abstract
The aim of the present study was to assess prognostic value of serum ST2 in patients with NSTE-ACS. The study is a prospective cross-sectional observational study that included 50 patients who were presented to specialized medical hospital, Mansoura University and El Mahalla Cardiac Centre by symptoms and signs of NSTE-ACS within the time period of October 2019 to October 2020. Electrocardiography, transthoracic echocardiography and blood samples from all the study population were withdrawn at admission to assess serum ST2 levels and the study patients were followed up for one month after hospital discharge for detection of major adverse cardiac events as regard cardiovascular mortality, rehospitalisation, recurrent chest pain, dyspnoea and arrhythmias. The studied patients were divided according to serum level of ST2 tests into two groups, group A (ST2 level<160ng/ml) and group B (ST2 level>160ng/ml). Overall conclusions of the processed study are: In the present study of the patients, 12% died within 28 days. ST2 values were higher among patients who died, and ST2 elevation was shown to be associated with mortality. The cut-off value for ST2 was found to be 19.85 mg/mL with a 98.2% sensitivity and 93.01% specificity. In conclusion, there is a positive correlation between serum ST2 levels and 28-day mortality in NS-ACS patients. Further studies are required for verifying the results of our study High prevalence of serum ST2 levels was found in patients presented with NSTEMI more than patients presented with unstable angina. The relation of Serum ST2 levels and short-term outcome was statistically significant. The relation of Serum ST2 levels and dyspnoea was statistically significant. The relation of Serum ST2 levels and arrhythmias was statistically significant. The relation of Serum ST2 levels and rehospitalisation was statistically significant. The relation of Serum ST2 levels and coronary angiographic finding disease was statistically significant. High ST2 levels was more predictive of mortality and rehospitalisation, Dyspnoea, Arrhythmias, obstructive coronary artery disease on ROC curve analysis. A future large study with more prolonged follow up and several measurements of serum ST2 levels is suggestive for more evaluation of the relation of abnormal Serum ST2 on cardiovascular outcome in patients with NSTE-ACS.