الفهرس 
Diagnosis of Candidiasis in autistic spectrum disorderOnly 14 pages are availabe for public view
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Abstract
Autism spectrum disorder (ASD) is a category of neurodevelopmental disorders characterized by social and communication impairment and restricted or repetitive behaviors. Aim of the Work: to estimate the quantity of Candida in autism spectrum disorder (ASD) patients compared to normal children and to find the correlation between Candida colony count and severity of ASD. Patients and Methods: The study was carried out on 40 children, diagnosed as autism and 40 normal children as control group recruited from Pediatrics and adolescent Psychiatric Clinic at Ain Shams University Pediatrics Hospitals and Main Microbiology lab in Clinical Pathology Department of Ain Shams University. The study was conducted on a wide age group ranging from 3 to 14 years, (mean age of 6.30±2.40 years). There was male predominance with male to female ratio about 4:1. Results: The study revealed statistically significant higher mean of stool count in severe of autistic group compared to mild to moderate of autistic group, with p-value (p=0.041). There were 14 patients (60.9%) of them had C. Albicans; 2 patients (8.7%) of them had C. Glabrata; 6 patients (26.1%) of them had C.Krusie and one patient (4.3%) of them had C. Utilis among candida species. Conclusion: ASD is more common among male than female; ratio about 4:1. The high rate of intestinal colonization by Candida species in ASD children may represent a part of syndrome related to immune system disorders that may play a role in the pathogenesis of ASD. C. albicans was the predominant isolate than other non Candida albicans in ASD. The degree of candida colonization represented as quantitative colony count does not affect the severity of CARS among ASD patients.