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العنوان
Value of MRI in the Evaluation of Azoospermia /
المؤلف
Alwakeel, Abdelrahman Ahmed Abdelaziz.
هيئة الاعداد
باحث / عبدالرحمن أحمد عبدالعزيز الوكيل
مشرف / محمد عبدالنعيم سلام
مشرف / خالد أحمد النحاس
مشرف / علياء سيد شيحة
تاريخ النشر
2021.
عدد الصفحات
246 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب التناسلي
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة عين شمس - كلية الطب - الأمراض الجلدية و التناسلية و أمراض الذكورة
الفهرس
Only 14 pages are availabe for public view

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Abstract

Azoospermia is defined as the absence of spermatozoa in the ejaculate and is present in about 10%–20% of infertile men. It is classified as obstructive azoospermia (OA) or nonobstructive azoospermia (NOA). OA is caused by obstruction of sperm delivery route at any level (rete testis, efferent ducts, epididymis, vas deferens, and ejaculatory duct). NOA is caused by testicular failure to produce sperm due to various factors.
It is im¬portant to distinguish OA from NOA patients because OA is characterized by normal spermatogenesis; thus, those patients are good candidates for sperm retrieval techniques or sometimes for surgical reconstruction, whereas NOA patients should proceed directly to treatment with assisted reproduction techniques such as intracytoplasmic sperm injection.
In the current study we aimed to show the usefulness of magnetic resonance imaging (MRI) in the evaluation of in-fertile men and its ability to distinguish obstructive from nonobstructive azoospermia.. We included 20 azoospermic men (8 with OA & 10 with NOA), diagnosed after at least two semen analyses & confirmed by testicular biopsy, MRI was done to each patient with same protocol with measurement of both volume & ADC value for every testis.
 Our study revealed that Patients with NOA usually have atrophic tes¬ticles with high ADC values, whereas patients with OA have testicles of normal size with low ADC values based on testicular volume & ADC values, using a cutoff of ≥13.17ml & ≤1.05 ×10-3 mm2/s respectively, we were able to make a diagnosis of OA with a sensitivity of 100% and specificity of 83%.
 Also we find that abnormalities typical for the obstruction of the seminal tract (e.g., prostatic cysts, the absence of vas deferens, dilatation of ejac¬ulatory ducts or vasa deferentia) are found in patients with OA which may be amenable to surgical correction.
 On the basis of our preliminary data, TV and ADC might represent useful MRI parameters in the workup of patients with NOA by helping to predict the presence of spermatozoa after mTESE.