الفهرس 
Aim of the studyOnly 14 pages are availabe for public view
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Abstract
In conclusion, sarcopenia is prevalent in CKD. The present study showed that 25.9% of the patients with non-dialyzable CKD had sarcopenia. In addition, 55.2% of the patients on dialysis had sarcopenia. Regarding the predictors of sarcopenia, the present study showed that non-dialysis patients with sarcopenia had significantly lower hemoglobin, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), platelet count, lymphocyte count, platelet-lymphocyte ratio (PLR), and serum magnesium level. On the other hand, non-dialysis patients with sarcopenia had a significantly higher neutrophil count, neutrophil- lymphocyte ratio (NLR), and serum creatinine. These findings are very important as it confirms the need for interventions that aim to minimize risk factors are recommended in CKD patients. Nevertheless, further studies with rigorous design, large sample size and multiregional cooperation are required. Frailty is common in the older dialysis population and is associated with adverse outcomes, including death, hospitalization, falls, and fractures. Studies are required to determine whether interventions can improve frailty.The potential association between frailty of predialysis patients and higher risk of ESRD would suggest that early intervention may be effective, but it is also important to consider the dialysis population whose current functioning is extremely impaired Contributors to frailty in CKD patients include higher CKD severity, high body mass index, decrease in hemoglobin level, hyperkalemia and hypoalbuminemia. Sarcopenia is prevalent in CKD. These findings are very important as it confirms the need for interventions that aim to minimize risk factors are recommended in CKD patients. Nevertheless, further studies with rigorous design, large sample size and multiregional cooperation are required. The findings show a high prevalence of frailty in ambulatory chronic dialysis patients without a recent admission history. The frail phenotype is significantly associated with hospitalization and mortality. Therefore, we should pay more attention to the frailty status of patients, even those who appear to be in a good condition, to improve their morbidity and mortality.