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العنوان
Clinicopathological Studies on theAntitumor Activity of Some Medicinal Plants on Ehrlich Ascites Carcinoma Induced Mice /
المؤلف
Al-Ghobashy، Raneem Saad Fathy .
هيئة الاعداد
باحث / رنيم سعد فتحى الغباشى
مشرف / امنية السيد كيلانى
مناقش / ناريمان محمد مصطفى
مناقش / أسامة محمد على
الموضوع
Clinical Pathology.
تاريخ النشر
2020.
عدد الصفحات
205 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Veterinary (miscellaneous)
الناشر
تاريخ الإجازة
1/1/2020
مكان الإجازة
جامعة قناة السويس - كلية الطب البيطري - الباثولوجيا الإكلينيكية
الفهرس
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Abstract

This study was designed to evaluate the anti-tumor effect of two natural plant extracts (Moringa Olifera ”M.O” and Licorice, ”Li”) in female albino mice.The possible beneficial effects of MO and Li were also investigated in EAC mice.
This study was carried out using total one hundredfemalealbino mice weighting between (20-25) g. The animals were allowed to be acclimated for 2 weeks prior to experimental use. The animals were randomly assigned in six groups (each 8mice kept in a cage). The animals were kept in natural day light rhythm and temperature 24 ± 2°C and a relative humidity of 60 ± 5%. Mice were fed ad libitum control diet fulfill nutritional diet all over acclimation and experimental period. Six groups were as follow:
group I (Control group), mice injected with saline IP, group II (Moringa Control group), Normal control miceinjected with saline IP and received (500 mg/ kg b.wt) M.O oil extract for 2 weeks, group III (Licorice Control group), Normal control miceinjected with saline IP and received (500 mg/ kg b.wt) Li oil extractfor 2weeks, group ΙV (EAC group), EAC injected mice with 2.5×106 Ehrlich cells by IP route that gavaged corn oil daily for 2 weeks, group Ѵ (EAC+MO group), EAC mice which were injected 2.5×106 Ehrlich cells by IP route treated next day with daily M.O oil only in adose of 500mg/kg body weightfor 2 weeks, group ѴΙ (EAC+Li group),EAC mice which were injected 2.5×106 Ehrlich cells by IP route treated next day with daily Li oil only in adose of 500mg/kg body weightfor 2 weeks. Both M.O and Li were administrated by oral gavage.
Body weights were determined weekly through 2 weeks. After 1 and 2 weeks of treatment by M.O and Li.Blood samples were collected in duplicates .