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Abstract The aim of this study was the comparison of central corneal thickness using anterior segment Optical Coherence Tomography Versus Ultrasound Pachymetry Versus Orbscan. The study included total number of 60 eyes from 30 cases recruited from Nour El Ein Hospital and Tanta university hospital from April 2018 to March 2019. All the included cases were subjected to full history taking and full ophthalmological examination. Three different measurements of the central corneal thickness (Maximal, Minimal and average) were taken from all the cases by the three devices (Ultrasound pachymetry, OCT and Orbscan). The results of this study showed that there was no statistically significant difference mean minimal measurement of the central corneal thickness as measured by the three devices (544.20±37.37 μm, 537.60 ± 33.74 μm and 547.40 ± 31.62 μm for the ultrasound pachymetry, anterior OCT and orbscan respectively). Also, this study showed that there was a statistically significant difference in the mean the maximal measurement of the central corneal thickness as detected by the three devices (528.47 ± 37.96 μm, 516.73 ± 41.96 μm and 537.80 ± 31.44 μm for the ultrasound pachymetry, anterior OCT and orbscan respectively). Within the same context, the results of this study showed that there was a statistically significant difference in the average central corneal thickness as measured by the three devices (532.60 ± 37.75 μm, 513.93 ± 44.34 μm and 539.67 ± 28.70 μm for the ultrasound pachymetry, anterior OCT and orbscan respectively). |