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Abstract BACKGROUND: Bronchial asthma is an inflammatory lung disease characterized by hyper-responsiveness and bronchoconstriction. Beta2 agonists are bronchodilator drugs that possess anti-inflammatory properties.AIM: The present study aimed to investigate the anti-inflammatory and antioxidant effects of short-acting (salbutamol) and long-acting (bambuterol) as beta2 agonists combination. Also, the effect of these drugs, singly and in combination with prednisolone was measured in asthma-induced rats in both lung tissue and broncho-alveolar lavage. |