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العنوان
Synthesis, Thermal, Spectroscopic and Biological Studies of Some New Thiazole Metal Complexes \
المؤلف
Rizk,Mariam Girgis.
هيئة الاعداد
باحث / مريم جرجس رزق
مشرف / عادل عباس أحمد عماره
مشرف / عزة على أبوحسين
مشرف / مها ربيع أبوسريع
تاريخ النشر
2021
عدد الصفحات
xx,325p.:
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الكيمياء
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة عين شمس - كلية التربية - قسم الكمياء
الفهرس
Only 14 pages are availabe for public view

from 392

from 392

Abstract

Synthesis of three different ligands derived from 2-amino-4-phenyl thiazole with acetylacetone (HL1), dimethylphthalate (L2) and methylsalicylate (HL3). The three ligands, HL1, L2 and HL3, were reacted with Cr(III), Fe(III), Co(II), Ni(II), Cu(II), Zn(II) and Ag(I) metal ions to synthsize their corresponding complexes. from the study, HL1 and HL3 were rearranged to enol form due to the keto-enol tautomerism, where the enol forms are more dominant. The structures of HL1, L2 and HL3 ligands and the newly synthesized complexes were characterized by elemental analysis, IR, UV-Visible, 1H-NMR, ESR and Mass spectral data, in addition to thermal gravimetric analysis (TGA), magnetic and molar conductance measurements. Some of the metal complexes were tested in vitro against breast cancer (MCF-7) for HL1, L2 ligands and human colon carcinoma cells (HCT-116) for HL3 ligand. For antimicrobial activities, HL1, L2 and HL3 ligands and their metal complexes were evaluated.