الفهرس 
Cancer treatmentOnly 14 pages are availabe for public view
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Abstract
Cancer is one of the deadliest fatal diseases, being the world’s leading cause of death. ‘Cancer’ is a catch-all word used to describe a set of diseases marked by autonomous expansion and somatic clone propagation. Chemotherapy, radiotherapy, hormone therapy, and surgery are the conservative alternatives to cancer therapy.
Ehrlich Ascites Carcinoma (Ehrlich cells, EAC), a spontaneous murine mammary adenocarcinoma is a well-established model in tumor biology. EAC model has generally been utilized to examine tumor pathogenesis and development of anti-tumorigenic agents.
A number of experiments are going on to develop compounds with minor side effects. Coumarins and aza-coumarins were reported to exhibit negligible or mild side effects. They exhibit a wide range of pharmacological activity like anticancer, antibacterial, antifungal, antioxidant, anti-inflammatory agents and immune stimulatory.
Coumarins and aza-coumarins exhibited antitumor activities at different stages of cancer formation through various mechanisms, for example blocking cell cycle, inducing cell apoptosis, and inhibiting the DNA-associated enzymes, such as topoisomerase.