![]() | Only 14 pages are availabe for public view |
Abstract Hydrogen sulfide (H2S) is endogenously produced from sulfur containing amino acids, including homocysteine and exerts neuroprotective effects. It is recognized as one of three gasotransmitters in mammals. • Aim of the work: In this study we analyzed the effects of the H2S donor sodium hydrosulfide (NaHS) on ethanol oxidative stressed rats. • Materials and methods: 50 albino male rat were stratified into five groups group I: (control group) Rats given saline per os with doses equal to that used in the experiment. group II: (ethanol treated group): were gavaged 56% solution (v/v) of ethanol 10ml/kg intragastrically. group III: were gavaged ethanol 10ml/kg/day intragastrically plus low dose of NaHS, 1mg/kg/ day/ ip) group IV: were gavaged ethanol 10ml/kg/day intragastrically pluse moderate dose of NaHS 2mg/kg /day/bw/ ip) group V: were gavaged ethanol 10ml/kg/day intragastrically plus high dose of NaHS 3mg/kg/ day/bw /ip). |