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العنوان
The effect of warm ischemia on the renal function recovery in open and laparoscopic partial nephrectomy :
المؤلف
Awad, Mohamed Tharwat Mohamed.
هيئة الاعداد
باحث / محمد ثروت محمد عوض
مشرف / حسن أبوالعنين
مشرف / أحمد ممدوح شومه
مشرف / محمد عبدالحميد أبوالغار
مشرف / أحمد محمد مصطفى الشال
مناقش / محمد رشدي بدرالدين
مناقش / نصر أحمد التابعي
الموضوع
Kidneys. Kidneys - Physiology. Surgery.
تاريخ النشر
2021.
عدد الصفحات
online resource (126 pages) :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
جراحة المسالك البولية
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة المنصورة - كلية الطب - قسم جراحة المسالك البولية
الفهرس
Only 14 pages are availabe for public view

from 129

from 129

Abstract

Patient presented to outpatient clinic with renal mass, were asked to participate in our study, when they met the inclusion criteria. The participant were divided into group A(OPN) and group B(LPN).patient were evaluated preoperatively with laboratory as well as radiological investigation (contrast CT, DCMI, renogram). Preoperative parameters , tumor characters and GFR were comparable between the groups. Intra-operative and post-operative events were recorded and compared between two groups. Intraoperative blood loss, hospital stay and analgesic dose were lower in favor of LPN (p< 0.001). As most of other series, ischemia time was lower in OPN (p< 0.001). GFR was recorded at 4 week and 4 month postoperative by DCMI and renogram in both groups. At 4 weeks, The GFR declined by 18% and 27% by DCMI and renogram, respectively, in open group. While, in LPN group, the percentage of GFR decline by DCMI was 15% and 24% by renogram. These measures were not-significant between two groups. At 4 month, the kidney recovered and the decline between two groups was insignificant. According to ischemia time (IT), GFR of PN with IT > 30 min (13 patient) and PN with IT <30 min (92) were compared which showed no difference at 4 week and 4 month. Conclusion : Laparoscopic partial nephrectomy is feasible, effective and comparable to open partial nephrectomy in management of moderate complex renal tumour (T1 and T2a). Hot ischemia is effectively tolerated by renal function even more than 30 minute. There is no difference between open and laparoscopic partial nephrectomy in this aspect. Dynamic contrast MRI could be used as single tool for both anatomical and functional evaluation of the patients with RCC in preoperative assessment and during follow up.