الفهرس | Only 14 pages are availabe for public view |
Abstract Female sexual dysfunction is a common problem with detrimental effects on woman‘s quality of life. It is defined as disorders of sexual desire, arousal, orgasm, and sexual pain, which lead to personal distress. Female sexual dysfunction has an economical and societal impact. The etiology of sexual dysfunction is frequently multifactorial as it relates to general physical and mental well-being, quality of relationship, past sexual functioning, social class, education, employment, life stressors, personality factors, the presence of a sexual partner, and partner‘s age and health. Furthermore, ovarian sex steroids have a major impact, and their decline has been found to be associated with an increased incidence of FSD. Androgens are believed to play a key role particularly in centrally guided aspects of sexuality such as desire arousal and sexual responsiveness. The effect of testosterone depends on the exposure of and the sensitivity of the AR. It has been shown that CAG trinucleotide repeat polymorphism in the AR gene has an impact on AR functional capacity in men. However large studies are lacking on the impact of this polymorphism on female sexual function. The aim of this study was to determine the prevalence and risk factors affecting FSD and the association between androgen receptor polymorphism and female sexual function. To elucidate our aim, all patients included in this study completed a questionnaire, which included the sociodemographic and |