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Abstract Evidence-based public health (EBPH) is the cornerstone in decision making process. Economic evaluation provides evidence for proper implementation of the intervention and enhance the sustainability of its effects with a focus on the costs and expected outcomes. It is considered as an integral component of public health evidence. Health Economic evaluation is defined as “the comparative analysis of alternative courses of action in terms of both their costs and their consequences”. There are two types of economic evaluation either partial or full. Regarding, partial economic evaluation, it focuses on evaluation of a certain intervention or disease but does not involve a comparison with another options. It includes two main types of economic studies: the cost of illness analysis and the program cost analysis. As regards the full economic evaluation analysis it compares the costs and outcomes among competing alternatives. It includes four types of studies: cost-minimization analysis, cost- benefit analysis, cost-effectiveness analysis and cost-utility analysis. There are two main categories of decision modeling cohort models and simulation models. Both infectious and chronic diseases (either communicable or non-communicable) are of great concern from the perspective of health economics. They result in productivity loss, morbidity and mortality that end by life loss. Additionally, in most circumstances the risk factors for these diseases are preventable and several cost-effective measures are available for their control. |