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العنوان
COVID 19 Related Multisystem Inflammatory Syndrome in Children Admitted to PICU in Ain Shams University Hospitals/
المؤلف
AboBakr,Ahmed Mohamed Hessain
هيئة الاعداد
باحث / أحمد محمد حسين أبوبكر
مشرف / حنان محمد ابراهيم
مشرف / نيفين ممدوح حبيب
مشرف / سندس محمد مجدي
تاريخ النشر
2021
عدد الصفحات
106.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة عين شمس - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

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from 106

Abstract

mean of 128(18), hypotension with mean of 80(5.7) for systolic blood pressure & mean of 42(6) for diastolic blood pressure, spo2 mean 94.5(2), high grade fever of mean 39(0.6) and SOFA score mean of 9(2). KD-like features were seen in many patients (skin rash in 55.6%, conjunctivitis in 46.7% and Cardiovascular abnormalities were seen in 100% e.g. (myocardial dysfunction, valvular regurgitation, coronary dilatation, pericardial effusion and shock). In our patients, 13 patients (28.9%) had significantly severe comorbid conditions, like (hematologic e.g. ALL, Cardiac e.g. ASD&VSD, Endocrinologic e.g. Diabetes mellitus). Our MIS-C patients had signs and symptoms of an inflammatory state and we believe that steroids played an essential role for those who recovered.
Conclusion: MIS-C is a hyper-infammatory syndrome affecting multiple organs and is triggered by SARS-CoV-2 infection. It is usually seen 2–4 weeks following infection. Adaptive immune mechanisms have a major role to play in pathogenesis of this condition.