الفهرس 
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Abstract
Hemolytic uremic syndrome (HUS) is the most frequent cause of acute kidney injury in children. HUS is a systemic microangiopathy characterized by acute hemolytic anemia, thrombocytopenia, and renal failure. The percentage of HUS patients presenting with chronic renal complications shows variations in different centers and communities due to variations of sample size, different duration of observation and follow up and variations on treatment regimens. For this reason, this study was conducted to study the characteristics, pathology and outcome of children with hemolytic uremic syndrome and to study the possible correlation between different variable and the outcome of hemolytic uremic syndrome This combined prospective and retrospective study was conducted at MUCH and included 150 patients from both the newly diagnosed cases with HUS over one year in MUCH in addition to old cases diagnosed as HUS in MUCH. After obtaining an informed consent from newly studied cases and study approval by the institutional review board, Mansoura Faculty of medicine the cases who were newly diagnosed underwent (or the archives of the old cases were reviewed) to obtain data about the history of the disease, clinical examination, full laboratory investigations, abdominal ultrasonography and determination of the final outcomes. The outcomes included the fate of the cases after treatment as either full recovery, development of CKD or death