الفهرس 
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Abstract
Uveitis is a sight-threatening inflammatory disease affecting the uveal layer of the eye. The condition is frequently idiopathic but about 60 causes of uveitis have been described. It may lead to irreversible visual loss if not treated properly in a timely manner. Despite considerable progress in the understanding of the mechanisms involved in the etiopathogenesis of uveitis and the availability of better and more accurate diagnostic techniques, the cause of many cases of uveitis still remains undetermined. Several epidemiological studies about the patterns of uveitis have been reported worldwide from different geographic regions and ethnic populations. These published reports have demonstrated variability in the patterns of uveitis among different geographic regions and ethnic populations. Knowledge about the pattern and differential diagnosis of uveitis based on regional variation of the disease is essential and helpful in facilitating the diagnosis and management. The aim of this study was to evaluate the demographic characteristics and clinical features of adult patients with uveitis in Mansoura Ophthalmic Center. This was a cross sectional study conducted on 411 eyes of 254 adult patients attending uveitis outpatient clinic of Mansoura Ophthalmic Center in two years from July 2019 to June 2021. The current study revealed the following results : • Mean age was 36.48 ±11.24 years. • Most of the studied cases had age more than or equal to 40 years (65.4%), while only 34.6% of which had age from 18 to 40 years. • Male to female (M/F) ratio was 47.6/52.4. • Seventy five percent of the study cases were from Dakahlia governorate followed by Gharbia (11%) then Kafr ELsheikh (6.7%) with minor percentages from Damietta, Sharkia, Alwady Aljadid, Albehira, Sohag, Ismailia and Cairo. • The majority of the studied cases were bilateral (61.8%), while only (38.2%) were unilateral. • The percentage of non-infections uveitis /infectious uveitis was 89.4 /10.6. • Most common etiologies of non-infections uveitis in the present study were Behçet’s diseases (30.3%), idiopathic (19.3%), Vogt Koyanagi Harada (16.1%), AS (15%). • Most common etiologies of infections uveitis in the present study were trematode induced uveitis (4.3%), herpetic uveitis (2.4%), toxoplasmosis (2.0%), TB (1.6%) and brucella (0.4%). • The most common type of uveitis was anterior uveitis (57.9%) followed by panuveitis (22.1%), posterior uveitis (17.8%) and intermediate uveitis (2.2%). • The mean BCVA of the studied cases was 0.797±0.77 LogMAR. • Most of cases (43.8%) had vision equal to or better than (6/12), followed by severe vision loss (vision ≤6/60) (31.4%), then moderate vision loss (vision from 6/18 to 6/36) (21.4%) and lastly total blindness (3.4%). • Macular edema (36.8%), cataract (26.8%), dense vitritis (18.2%) were demonstrated to be the most common causes of vision loss. • Types of uveitis were demonstrated to be significantly correlated with the degree of visual loss. Most of AU cases had no vision loss, while nearly half of intermediate uveitis, posterior uveitis and panuveitis had severe vision loss. • Types of uveitis were demonstrated to be significantly correlated with the reversibility among studied cases. Most of anterior uveitis and posterior uveitis cases were reversible, while half of intermediate uveitis and nearly half of panuveitis were irreversible. Conclusion : Uveitis in Egypt affects working age group (36.48 ±11.24 years) with slight female predominance. Bilateral uveitis is the most common presentation. Anterior uveitis is the most common anatomic form of uveitis in Egypt. The etiologic diagnosis of non-infectious uveitis should focus in particular on Behçet’s disease, Vogt koyanagi Harada and ankylosing spondylitis, while infectious causes include trematode induced, herpetic and toxoplasmosis. Most of cases have reversible cause of vision loss and macular edema is the commonest cause of vision loss.