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العنوان
Assessment of pericardial fat volume and carotid intimal thickness as risk factors for developing coronary atherosclerosis using multi detector computed tomography /
المؤلف
Elkordy, Mahmoud Moustafa Mahmoud.
هيئة الاعداد
باحث / محمود مصطفى محمود الكردي
مشرف / أحمد مصطفى محمد
مشرف / هبة الله محمد يسرى النجار
مشرف / أحمد مصطفى محمد
تاريخ النشر
2022.
عدد الصفحات
169p. :
اللغة
العربية
الدرجة
ماجستير
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2022
مكان الإجازة
جامعة عين شمس - كلية الطب - قسم الأشعة التشخيصية
الفهرس
يوجد فقط 14 صفحة متاحة للعرض العام

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from 169

المستخلص

ABSTRACT
Background: The real visceral fat deposit of the heart is epicardial adipose tissue, which exists directly on the epicardial surface of the myocardium and is totally confined within the pericardial sac. Because the coronary arteries and their major branches are embedded in fat, a local contact between a metabolically active epicardial adipose tissue and the coronary vasculature was possible. Carotid artery increased intimal thickness is the initial step within the process of atherosclerosis which is a major causes of stroke, Myocardial infarction and other coronary and arterial diseases.
Aim of the Work: To study the relation between pericardial fat volume measurements in Multi and detector computed tomography ‘MDCT’ with carotid intima-media thickness in duplex study for detecting the risk of developing coronary atherosclerosis.
Patients and Methods: This retrospective study was carried out at Radio diagnosis department; in Shams University Hospitals (ASUH) during the period from January 2021 till June 2021 upon 30 patients; their age ranged from 37 to 78 years old with mean age of 60 years. Patients were either self-referred or referred by a physician for follow up or investigate CAD. All patients were already performed coronary CT angiography. They were evaluated for: (I) Coronary calcium score. (II) Pericardial fat volume. (III) Degree of atherosclerosis, then Carotid duplex study done for evaluation of the carotid intimal thickness.
Results: we demonstrated that pericardial fat volume MDCT has a positive significant strong correlation with CAD (P. Value <0.001). Post-hoc Bonferroni test done regarding the obtained data and had significant difference between: Moderate and Severe Vs. all groups, that’s mean a significant difference between moderate group with minimal or mild. And a significant difference between severe and minimal or mild.
Conclusion: Multi-detector CT and Carotid duplex examination both were considered a good non-invasive tools for evaluation of PAT volume (mean for unremarkable to minimal degree, volume about 94 ± 14.73 cm3) and CIMT (mean unremarkable to minimal degree,thickness about 0.67 ± 0.06 mm) respectively. Both were considered as an independent but significant and positively proportionate correlated risk factors for coronary atherosclerosis, so it is recommended to fix both tests to be an evaluating / screening tool for any patient with suspected or confirmed CAD to evaluate the risk and severity.