الفهرس 
Hand-Foot SyndromeOnly 14 pages are availabe for public view
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Abstract
Hand-foot syndrome is one of the most commonly reported dermatological adverse effects of chemotherapy. It leads to treatment interruption, dose modification, and affects the quality of life of cancer patients. This study aimed to assess and interpret the possible mechanisms by which capecitabine induces hand-foot syndrome and evaluate the role of collagen and quercetin-incorporated collagen matrices in the prevention of hand-foot syndrome. Methods: This experiment was conducted on 40 male Sprague Dawley rats allocated to 4 equal groups. group 1 served as normal control and received a vehicle of distilled water by oral gavage.