الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Dopamine is a very significant neurotransmitter accountable for different roles in the human body, including regulating impulses, endocrine regulation, and motivational control. In this research, we developed an effective biosensor for the prediction of dopamine utilizing spherical gold nanoparticles. Gold nanospheres have been prepared using Turkevich Method and characterized through static light scattering, TEM, dynamic light scattering, and zeta potential measurements. Static laser scattering used a laser diode with wavelength 650 nm and power 5mW. The biosensor is beneficial in detecting dopamine concentrations up too 200 nM. This detection process relies on the aggregation of gold nanoparticles which induce a shift in the optical properties as the color of the solution change from deep red to blue. Since dopamine concentrations raise the mean diameter of gold nanoparticles recorded by dynamic light scattering instruments increase, suggesting the existence of aggregated nanoparticles. TEM images indicated aggregation when dopamine concentration increased. This method was linear between 200 nM and 2 μM and the correlation coefficient (R2) was 0.995. This method produces a fast effective unique colorimetric-GNPs probe for the detection of dopamine in any biological samples.