الفهرس | Only 14 pages are availabe for public view |
Abstract Modified Hench’s bioglass divided by two systems of the basic composition xAg2O (45 B2O3, 24.5 CaO, 24.5 Na2O, 6 P2O5) as (x= 0.1, 0.2, 0.4, 0.6, and 0.8 wt.%) for first system was successfully prepared via the melt quenching route. Immersion in phosphate solution (PS) varying times (1→4 weeks) was used to assess the in-vitro behavior of the bulk glassy samples with different silver oxide content. X-ray diffraction XRD, scanning electron microscopy (SEM), and other spectroscopic measurements including Fourier transform infrared (FT-IR) analytical techniques and UV/visible optical measurements before and after prolonged immersion times were used to estimate the bioactive behaviors and to explain the efficiency of bone-bonding. Besides, antimicrobial tests against pathogenic grams were examined and silver ions show varying levels of action against certain bacteria. It was noticed that prolonged immersion periods cause distinct variations that link the vibrational bands because of a preferential attack or ion exchange and modifier replacement by silver ions in the glass network causing the hydroxyapatite formation as an indication for bone-bonding ability. Antimicrobial experiments reveal that studied material can be used efficiently as an antibacterial agent. Second system Samples of Hench’s bioglass of the composition Borate glasses have the formula according to, xAg2O and xCeO2 and (45 B2O3, 24.5 CaO, 24.5 Na2O, 6 P2O5) as (x= 0.1, 0.2, 0.4, 0.6, and 0.8 wt. %) added overweight to the batch, whereas Na2O and CaO were introduced in the form of their respective carbonates while P2O5 was added in the form of ammonium dihydrogen phosphate (NH4H2PO4) were prepared. In vitro cases of the bulk glass samples with high concentration of silver oxide and cerium oxide content were tested by immersion in phosphate solution for different periods of time (1→4 weeks). Formation of a hydroxyl carbonate apatite (HCA) layer on samples surfaces and bioactivity, was confirmed by XRD, FTIR, SEM and microbial test while presence of Ce2+/Ag2+in the glasses before and afterphosphate solution (PS)) immersion was determined. The general goal of the extended research is to justify the bone-bonding efficiency when both X-Ray diffraction and immersion durations are present. Experiments show that FTIR spectra are stable, but prolonged immersion times induce distinct variations that touch the vibrational bands as a result of ion exchange or preferential attack and substitute of modifiers by silver and cerium ions for the system of samples, resulting in the formation of hydroxyapatite as a bone-bonding ability indicator. The antimicrobial test reveals certain differences in the activity and quantity of silver ions added in the presence of cerium ions against various bacteria. |