الفهرس 
InfertilityOnly 14 pages are availabe for public view
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Abstract
Background: Ovarian hyperstimulation syndrome (OHSS) is a complication of the fertility treatment, assisted reproductive technology (ART), which depends on pharmacological ovarian stimulation to increase the number of oocytes and therefore embryos available during. Severe OHSS is a potentially life-threatening, grave complication and occurs in about 2%-6% of IVF cycles resulting in hospitalization in about 1.9% of cases resulting in significant morbidity and rarely, mortality due to thromboembolic disease, adult respiratory distress syndrome, and hepatorenal failure. Of the various strategies used for the prevention of OHSS, the most effective strategy to date is the use of Gonadotropin Releasing Hormone agonist (GnRHa) as trigger in antagonist cycles, which markedly reduces its occurrence Patients and Methods: The current study was performed on 200 women who underwent ICSI at Ain Shams University hospitals and other private centers the 200 patients were randomized into the 2 groups one group received GnRHa trigger with cycle segmentation and the other received Human chorionic gonadotropin (HCG) as trigger of ovulation. Aim of the Work: The aim of this study was to compare the effectiveness of GnRHa versus HCG trigger to reduce OHSS. Results: 20% of patients in HCG group (N:20) developed OHSS and 3%. (N:3) developed moderate to severe OHSS, while in GnRHa group only 3% of patients (N:3) developed OHSS with only one patient developed moderate OHSS. Conclusion: using GnRHa trigger has the advantage over HCG trigger regarding OHSS rate with lower incidence of OHSS rate among GnRHa group.