الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
The peripheral cornea is different from central cornea in morphologic and immunologic characteristics make it more vulnerable to inflammatory reactions and necrosis. Peripheral corneal ulcer is caused by various infectious and non-infectious ocular and systemic diseases. Early diagnosis and prompt treatment prevent blindness due to this devastating inflammatory condition. This study aimed to evaluate different modalities for management of peripheral corneal ulcer. This study was done on the patients who admitted the cornea unit of the Tanta University Ophthalmology Hospital, a tertiary referral center from October 2019 to March 2020 suffered from peripheral corneal ulcer. According to the culture and sensitivity results, the specific antimicrobial drug was prescribed for each case depending on the highest organism sensitivity (highest number of positive marks in the culture and sensitivity report). In this study, surgical treatment such as amniotic membrane transplantation (AMT) and tectonic keratoplasty were indicated as adjunctive treatment in the cases that resistant to its suitable protocol of treatment or deteriorate within two week. In our study, 14 of 30 eyes were responded to medical treatment (group A) with complete epithelial healing as time of healing ranged from 2-6 weeks with a mean of 3.36 ± 1.34. On the other hand, 16 of 30 eyes were resistant to its suitable protocol of treatment or deteriorate within two week and underwent surgical interference as adjunctive treatment (group B). 7 eyes were managed by AMT and 9 eyes were treated with tectonic keratoplasty. The outcome was anatomical success observed and restored the ocular integrity after treatment of all eyes with resolution of the inflammatory signs. Time of healing ranged from 4-14 weeks with a mean of 9.38 ± 3.91.