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Abstract Background: Heart failure (HF) is a major and growing public health problem around the world and RV dysfunction is associated with adverse outcomes in patients with HFrEF. As compared with the left ventricle (LV), the unique features of the RV and its complex geometry that make it difficult to find a simple, reliable measure for assessment of its function. 2D Speckle tracking echocardiography allows an accurate assessment of segmental myocardial deformation. In LBBB, Abnormal electric conduction and activation asynchrony lead to early active leftward contraction of the septum within the isovolumic contraction time, followed by lengthening, while the late-activated lateral wall starts to contract. Abnormal motion of the ventricular septum has been described by echocardiography and is referred to as a septal flash (SF). Objectives: This study was designed to evaluate RV function in patients with HFrEF and LBBB using 2D speckle tracking echocardiography based strain imaging. Methods: 40 patients were enrolled in the study who were divided into 2 groups: 20 patients with HF and complete LBBB and 20 patients with HF and non LBBB. Participants in the study were subjected to full history taking, thorough clinical examination, 12 leads ECG, 2D echocardiography. 2D echocardiographic analysis: for Calculation of FAC as follows from this equation: (RVEDA-RVESA/RVEDA) X 100. M-mode study for measurement of EF, interventricular septum thickness, LV end diastolic and systolic internal diameters, posterior wall thickness, fractional shortening, aortic root diameter and |