الفهرس 
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Abstract
Summary
Diabetic retinopathy is the most frequent cause of new cases of blindnessamong adults aged 20–74 years.
Duringthefirsttwodecadesofdisease,nearlyallpatientswithtype1diabetesand>60%ofpatientswithtype2diabeteshaveretinopathy.Inthe Wisconsin Epidemiologic Study of Diabetic Retinopathy (WESDR), 3.6% ofyounger-onset patients (type 1diabetes) and 1.6% of older-onset patients(type 2 diabetes) were legally blind. In the younger-onset group, 86% ofblindness was attributable to diabetic retinopathy. In the older- onset group,in which other eye diseases were common, one-third of the cases of legalblindness were duetodiabetic retinopathy.
Therearethreemainstagesofdiabeticretinopathy:Non-proliferativeretinopathy is an early form of the disease, where the microaneurysms leakfluid or bleed, Macular oedema is a swelling of the macula, caused by theleakage of fluid from retinal microaneurysms. It can damage central vision.About half of all people with diabetic retinopathy will develop DME andProliferative retinopathy is an advanced form of the disease and occurs whenretina became ischemic and new vessels grow that can result in VitreoushemorrhageorRetinaldetachment.
This case control study was conducted on 30 eyes of diabetic patients withdiabetic retinopathy and 30 control eyes of the same age and sex matchedgroupattendingophthalmologydepartment atBeni-Suef universityhospital.
• Toassesssubfovealchoroidalthicknessindiabeticpatientswithdiabeticretinopathy.
• Tocomparethechoroidalthicknesstothenormalaverage.
Themainresultsof thestudyrevealedthat:
Thecentralmacularthicknessof casesrangedfrom192to403μmwithmean±SDwas270.63±39.97.Thesubfovealchoroidalthicknessrangedfrom214to391withmean±SDwas301.57±46.18.Themeanmeanerrorofrefractionwas-0.229±3.28whilethe mean intraocularpressurewas16.63±2.78 mm/Hg.
Therewasstatisticallynosignificantdifferencebetweenthetwogroupsregardingage(p=0.391).Also,therewasnostatisticallysignificantdifferencebetween the two groups regarding gender(p=0.795).
Centralmacularthicknesswas significantly higher in diabeticgroup compared to controlgroup (p=0.008).
Subfovealchoroidalthicknesswassignificantlylowerindiabeticgroup compared to controlgroup (p<0.001).
Subfovealchoroidalthickness was significantly positivelycorrelatedwithcentralmacularthickness(r=0.386,p=0.035)indiseasedgroup.
Based on our results we recommend for further studieson larger number of patientsandlongerperiod offollowup to emphasizeour conclusion.