الفهرس 
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Abstract
The present study aimed to compare the efficacy of percutaneous coronary intervention (PCI) following successful thrombolysis with Streptokinase versus primary angioplasty in patients with ST-segment elevation myocardial infarction (STEMI). The study included 100 STEMI patients. They were divided into two groups. group A : comprised of 50 patients who had primary PCI as a reperfusion strategy, group B : comprised of 50 patients who hadstreptokinase based pharmacoinvasive technique .In addition to the thorough history taking, clinical examination,ECG and Echocardiography for assessment of the primary outcome which was LV systolic function after angioplasty, assessed by 2D global longitudinal strain (GLS) using speckle tracking echocardiography (STE), as well as 2D LVEF using Simpson’s biplane method. Comparison between the two groups on the basis of outcome were done. Our study showed that there is a significant improvement of LV function as assessed by GLS and ejection fraction in both groups at short-term follow-up. Primary PCI remains the optimal reperfusion therapy when timely administered. As, primary coronary angioplasty had a more significant clinical benefit when compared with IV streptokinase therapy as regard curing the myocardial infarction.