الفهرس 
ACKNOWLEDGEMENTSOnly 14 pages are availabe for public view
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Abstract
Self-poisoning is among the commonest methods used by individuals to commit suicide which are variable from country to country even within the same country. Self-poisoning with medication, household substances and alcohol are commonly used in high-income countries while in low-income countries pesticides are common agents in suicide which are easily accessible materials This prospective observational cross-sectional study conducted from 1st January 2020 to 31st December 2020 to find out the prevalence of suicidal poisoning in Assiut university hospitals, identify the factors contributing to its occurrence, know the substances most commonly used among different age groups and the outcome of these suicide attempts as well as their motivation Over the mentioned period, data were collected including sociodemographic criteria, type of poison used, the severity of cases according to poisoning severity score, reasons for committing suicide, and the outcomeThe suicidal poisoning cases who admitted to emergency units of Assiut University hospitals were 303. They accounted for 25% of total admitted poisoned cases that reached 1200. Regarding the substances used in suicide attempts, it was found that pesticides were used in 69.6% of cases, especially AlP tablets in 65.4% of cases due to their easy accessibility and low price.The motivations behind these attempts, were owing to family problems (66.3%) followed by financial reasons (13.9%) and educational causes (12.2%).Female participants outnumbered males in 60.4%, and 49.9 % of enrolled cases were young aged persons (less than 20 years). The main victims of suicidal poisoning were singles, who resided in rural areas, and had low socioeconomic status, besides their low educational level and unemployment The present study illustrated that the seasonal variations of suicide attempts were 33% during Autumn and 25.4% during Winter. The mortality rate was 22.8% of enrolled cases. The time between ingestion of poisoning substances and hospital arrival was 2h in 46.5% of cases. Twenty-nine point four percent of cases had PSS grade 3 The main presenting symptoms were vomiting (70%) and abdominal pain (60.7%) and on examination, 24.4% of cases were shocked Regarding hospital stay, 48.2% of enrolled cases stayed in hospital for 24 hours. Only 34.3% of cases were admitted to ICU.Routine investigations were done, ABG results were acidotic in 34.7%, ECG was normal sinus in 56.4%, hyponatremia in 3.3%, hypokalemia in 6%, elevated liver functions and renal functions in 5.9% and 24.7% respectively Treatment including supportive management with fluids and oxygen followed by decreasing absorption of poisons using gastric lavage in combination with activated charcoal in the stomach was done while the using of antidotes was in some cases We found statistically significant relationship between the type of poison and point foursex; where females attempted suicide with therapeutic drugs and pesticides with percentage of 78.2% and 53.6%, respectively while the largest percentage of males (46.4%) committed suicide by pesticides. Moreover, pesticides, household agents and other poisons were significantly the most common used poisons in cases of intermediate education with percentage of 40.35%, 60% and 44.4% respectively while therapeutic drugs used by those of basic education at 41.0 % Significant relations were found between type of poison and occupation as suicidal cases of the non-working group used pesticides and other poisons with percentage of 40.7% and 66.7% respectively while 46.2% of suicide attempts by drugs occurred in students group. Moreover, higher frequency of suicidal poisoning by pesticides were in cases of low socioeconomic status versus higher frequency by therapeutic drugs in people of high socioeconomic status with statistically significant relation We found significant relation between PSS and type of poison as PSS grade 1 recorded in suicidal poisoning cases with pesticides, household agents, therapeutic drugs and other poisons with percentage of 43.6% ,100%, 70.5% and 55.6% respectively. Also, the PSS grade 1 recorded significantly in cured cases and discharged cases (on demand) with percentage of 66.8% and 71% respectively. While grade 3 encountered in 92.8% of dead cases.