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Abstract This study was conducted on fifty patients diagnosed clinically as dementia patients. They were 22 males and 28 females. Their age ranged between 50 and 79 years. The aim of this work is to study the role of magnetic resonance imaging and magnetic resonance spectroscopy in evaluation of dementia patients.All patients were subjected to full history taking and thorough clinical examination. Magnetic resonance imaging was performed at 1.5 Tesla MR system using a standard head coil. Imaging included conventional MRI and proton magnetic resonance spectroscopy. Proton magnetic resonance spectroscopy was done using multi-voxel technique.The study was conducted on thirty patients clinically diagnosed as dementia, 17 of the patient were AD dementia, 23 were vascular dementia and the remaining 10 were Parkinson disease dementia. By conventional MRI each patient was assessed for medial temporal lobe atrophy, Fazekas scale and NINDS-ARIEN criteria for vascular lesions and for the presence of abnormal findings in the substantia nigra.We found that the grade of medial temporal lobe atrophy was higher in patients with AD than in the other two types of dementia, still we found that this finding is not reliable when differentiating between dementia subtypes as in our study there were three out of seventeen patients with AD that did not show appreciable medial temporal lobe atrophy, while on the other hand two patients with VaD showed grade 4 on MTA scale. |