الفهرس 
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Abstract
The present study was conducted to evaluate the efficacy of cefquinome in treatment of broiler chickens experimentally infected with E. coli in addition determination of its residues using high performance liquid chromatography (HPLC) in both healthy and infected broilers.
(A) In vitro studies:
a- Isolation of E. coli:
Cultivation of sample of infected chickens on macConkey agar media, showed growth of pink (red) color colonies but on eosin methylene blue agar, showed green-metallic colonies after 24 hrs of incubation at 37º C.
b- Sensitivity of E. coli to cefquinome compared with other antibiotics (disc-diffusion method):
The results of sensitivity test showed that cefquinome had more potent inhibitory effect on E. coli than other antimicrobial agent tested.
(B) In vivo studies:
In our study, a total number of 200 one day old clinically healthy broiler chickens were randomly allocated into 4 equal groups (each one contained 50 chicks).