الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 133 |  |  |
| | | from | 133 | | |
Abstract
Toxoplasmosis is a major health problem that affects about 30-50% of human population worldwide. It has serious complications, especially in immunocompromised patients or congenitally infected newborns. The first line of diagnosis, the serological techniques, have many limitations, besides, some are not effective in many cases; as in immunocompromised patients or in diagnosis of congenital toxoplasmosis during pregnancy. Additionally, most of the time, they cannot be of a great value for follow-up of treatment or diagnosing very early infection. That is why a better method of diagnosis is needed. MicroRNAs (miRNAs) are non-protein-coding RNA molecules that have been discovered in 1993. Mature miRNAs can directly affect the expression of thousands of genes, by inhibiting protein expression via translational repression and/or mRNA degradation. So that, they have essential roles in regulating immune response outcomes. T. gondii-derived miRNAs have