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العنوان
Assessment the use of long acting insulin in management of DKA in pediatrics :
المؤلف
Mohamed, Gad Gamal Gad.
هيئة الاعداد
باحث / جاد جمال جاد محمد
مشرف / أماني كمال الهواري
مشرف / علي عبدالوهاب صبح
مناقش / هشام السيد عبدالهادي
مناقش / اشجان عبدالله الغباشي
الموضوع
Diabetes Mellitus. Diabetes Mellitus - Child. Acidosis.
تاريخ النشر
2022.
عدد الصفحات
online resource (145 pages) :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2022
مكان الإجازة
جامعة المنصورة - كلية الطب - قسم طب الاطفال
الفهرس
Only 14 pages are availabe for public view

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from 168

Abstract

Type I diabetes mellitus is considered one of the commonest metabolic and endocrine conditions occurring in childhood. The incidence of TIDM is elevating all over the world and it is estimated that nearly ninety thousand child are discovered per year.Blood glucose measurements are required for the diagnosis of DM. Besides, specific presentation, According to Fasting blood glucose of more than126 mg/dl or an RBG or two random blood glucose during a OGTT of more than two hundred mg/dl physician could discover DM. The biochemical criteria for the diagnosis of DKA are : •Hyperglycemia (blood glucose >11 mmol/L [≈200 mg/dL]). •Venous pH <7.3 or bicarbonate <15 mmol/L. •Ketonemia and ketonuria. The most serious clinical complication of DKA in childhood is cerebral edema, although other acute and chronic complications are not rare. The goals of therapy include; correction of dehydration, correction acidosis with reversing ketosis, restoring blood glucose to near normal, avoiding complications of the therapies, and identifying with treating any precipitating event. Our study design was randomized controlled trial, conducted on 100 DKA patients divided to two groups;50 patient received standard treatment regimen for DKA including continuous short-acting insulin infusion and IV fluids and 50 patient received standard treatment regimen for DKA in addition to their usual dose of long-acting insulin subcutaneously daily at night. We concluded that the use of long acting insulin beside short acting insulin in management of DKA was effective to hospital stay duration without increase the risk of hypoglycemia while, it needs close monitoring of potassium for fear of hypokalemia.